New inherited form of obesity and diabetes discovered
Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans.
A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington’s disease.
It is unclear what proportion of severe obesity and type 2 diabetes is caused by genetic disease.
Researchers at Imperial College London discovered the new defect by sequencing the DNA of an extremely obese young woman and members of her family. In addition to an increased appetite leading to severe weight problems from childhood, she had type 2 diabetes, learning difficulties, and reproductive problems.
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More articles Posted on: 03 July 2015